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Popular Malaysian soup can cause liver damage when mixed with medication

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July 13, 2022
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Popular Malaysian soup can cause liver damage when mixed with medication
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The impact of 4 totally different bak kut teh formulations on HepG2 cells after 48 h of publicity. A Formulation #1 confirmed vital toxicity earlier than dilution (p = 0.023), however demonstrated no vital toxicity as soon as diluted (p > 0.05). B Formulation #2 demonstrated vital toxicity with no dilution issue (p = 0.009), however none as soon as diluted (p > 0.05). C Bak kut teh Formulation #3 confirmed related toxicity when undiluted (p  0.05). D Formulation #4 was proven to be considerably poisonous undiluted (p Forensic Science, Drugs and Pathology (2022). DOI: 10.1007/s12024-022-00490-5

Researchers from the College of Adelaide have discovered {that a} well-liked soup, bak kut teh, has the potential to trigger liver failure by clashing with prescription medicine.

“Our crew studied the recipes of 4 regionally bought packet mixes of bak kut teh, in any other case often called meat bone tea,” stated Professor Roger Byard, George Richard Marks Chair of Pathology on the College of Adelaide. “When blended with liver cells, the components killed as much as 83% in a single concentrated soup system.

“Individuals have been warned for a while that natural medicines and therapies could have dangerous unintended effects that may embody vital liver harm. In uncommon circumstances this has required transplantation and even led to demise.

“For the primary time, a laboratory research by the College of Adelaide has proven that meals containing herbs, such because the soup bak kut teh, may be poisonous to liver cells.

“Individuals with underlying liver illness or who’re taking prescription medicines ought to be warned of this potential facet impact. All such preparations ought to embody correct labeling of the components till additional research might be undertaken to establish the particular natural substances which might be poisonous. Having the soup at house or at a restaurant could trigger harm to the liver.

“If sudden liver harm is encountered at post-mortem, info on doable latest ingestion of natural meals preparations ought to be sought, as routine toxicology screening is not going to establish the lively parts. Liver harm could due to this fact be induced not solely by natural medicines, however presumably natural merchandise contained in meals.”

The components of every of the soups various significantly from one label to a different.

They included:

  • Formulation one: Dried hawthorn
  • Formulation two: Goji berries, ginseng, bark, and dried mushrooms
  • Formulation three: Polygonatum odoratum, ligusticum chuanxiong, codonopsis pilosula, cinnamomum cassia, angelica sinensis, illicium verum, piper nigrum, and Eugenia caryophyllata
  • Formulation 4: Spices, pepper and salt

All formulations of bak kut teh demonstrated vital ranges of toxicity.

The outcomes of the checks have been revealed within the journal Forensic Science, Drugs and Pathology.


Highlighting the dangers posed by natural medicines to the Australian group


Extra info:
Susan M. Britza et al, Might natural soup be a probably unrecognized reason behind hepatotoxicity at post-mortem?, Forensic Science, Drugs and Pathology (2022). DOI: 10.1007/s12024-022-00490-5

Offered by
College of Adelaide


Quotation:
Standard Malaysian soup may cause liver harm when blended with medicine (2022, July 12)
retrieved 13 July 2022
from https://medicalxpress.com/information/2022-07-popular-malaysian-soup-liver-medication.html

This doc is topic to copyright. Aside from any truthful dealing for the aim of personal research or analysis, no
half could also be reproduced with out the written permission. The content material is offered for info functions solely.



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